Feeding the continuously growing world population is challenging, and edible insects offer a sustainable alternative to conventional sources of animal proteins.
As with any food source, the potential presence of hazardous organic chemicals, such as persistent organic pollutants (POPs), plasticizers and flame retardants (FRs), must be investigated to guarantee consumer chemical safety.
Here, we have investigated the contamination levels of several classes of organic compounds in edible insects. To evaluate their chemical safety, a dietary exposure risk assessment was then performed by combining the measured chemical contamination with the most recent food consumption data from local surveys.Insect samples, belonging to six orders (Orthoptera, Coleoptera, Lepidoptera, Hemiptera, Odonata, Hymenoptera) were purchased from five European and three Asian countries.
POPs and halogenated FRs were analyzed by gas chromatography-mass spectrometry (GC/MS) and organophosphorus FRs and plasticizers were quantified by liquid chromatography-MS/MS, according to validated protocols.
The overall levels of chemical contamination varied greatly among the insect orders and country of purchase, but they were generally low and comparable with other commonly consumed animal products.Here we show that, besides the activities during rearing, the industrial post-harvesting handling and addition of ingredients are supplementary factors influencing the chemical load of the final insect food-product.
Myo-Inositol |
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330153 | MedKoo Biosciences | 500.0g | EUR 350 |
Myo-Inositol |
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41350000-1 | Glycomatrix | 50 g | EUR 21.59 |
Myo-Inositol |
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41350000-2 | Glycomatrix | 100 g | EUR 44.84 |
Myo-Inositol |
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41350000-3 | Glycomatrix | 250 g | EUR 78.71 |
Myo-Inositol |
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41350000-4 | Glycomatrix | 5 kg | EUR 657.86 |
Myo-Inositol |
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41350000-5 | Glycomatrix | 1 kg | EUR 216.71 |
myo-Inositol |
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B7903-100 | ApexBio | 100 mg | EUR 129.6 |
myo-Inositol |
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B7903-500 | ApexBio | 500 mg | EUR 199.2 |
myo-Inositol |
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B7903-5000 | ApexBio | 5g | EUR 38 |
Description: A component of membrane phospholipids, glycosylphosphatidylinositol anchors |
myo-Inositol |
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GC4902-1 | Glentham Life Sciences | 1 | EUR 124.6 |
myo-Inositol |
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GC4902-100 | Glentham Life Sciences | 100 | EUR 22.4 |
myo-Inositol |
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GC4902-100G | Glentham Life Sciences | 100 g | EUR 62.4 |
myo-Inositol |
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GC4902-1KG | Glentham Life Sciences | 1 kg | EUR 180 |
myo-Inositol |
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GC4902-25 | Glentham Life Sciences | 25 | EUR 11.9 |
myo-Inositol |
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GC4902-250 | Glentham Life Sciences | 250 | EUR 41.4 |
myo-Inositol |
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GC4902-250G | Glentham Life Sciences | 250 g | EUR 84 |
myo-Inositol |
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GC4902-25G | Glentham Life Sciences | 25 g | EUR 48 |
myo-Inositol |
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GC4902-500 | Glentham Life Sciences | 500 | EUR 70.5 |
myo-Inositol |
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GC4902-500G | Glentham Life Sciences | 500 g | EUR 117.6 |
Myo-inositol |
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TBZ2449 | ChemNorm | 20mg | Ask for price |
myo-Inositol |
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I665995 | Toronto Research Chemicals | 10g | EUR 104 |
Description: 87-89-8 |
myo-INOSITOL |
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I703 | PhytoTechnology Laboratories | 100G | EUR 823.49 |
Myosin (Myo) Antibody |
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20-abx179001 | Abbexa |
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Active Myoglobin (MYO) |
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APA480Hu01 | Cloud-Clone | 10ug | EUR 252 |
Native Myoglobin (MYO) |
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RPU53472-100ug | Biomatik Corporation | 100ug | EUR 554.4 |
Native Myoglobin (MYO) |
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RPU53472-1mg | Biomatik Corporation | 1mg | EUR 2457 |
Native Myoglobin (MYO) |
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RPU53472-50ug | Biomatik Corporation | 50ug | EUR 445.5 |
Active Myoglobin (MYO) |
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RPU56321-100ug | Biomatik Corporation | 100ug | EUR 997.7 |
Active Myoglobin (MYO) |
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RPU56321-1mg | Biomatik Corporation | 1mg | EUR 3931.2 |
Active Myoglobin (MYO) |
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RPU56321-50ug | Biomatik Corporation | 50ug | EUR 604.8 |
Native Myoglobin (MYO) |
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NPA480Ra01 | Cloud-Clone | 10ug | EUR 180 |
Native Myoglobin (MYO) |
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4-NPA480Ra01 | Cloud-Clone |
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Description: Recombinant Rat Myoglobin expressed in: Rat |
Myoglobin (MYO) Antibody |
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20-abx100275 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx100276 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx100277 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx129941 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx130425 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx173666 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx173667 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx173668 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx173669 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx177665 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx177667 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx177668 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx104765 | Abbexa |
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Myoglobin (MYO) Antibody |
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20-abx104806 | Abbexa |
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Recombinant Myoglobin (MYO) |
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RPU54157-100ug | Biomatik Corporation | 100ug | EUR 578.6 |
Recombinant Myoglobin (MYO) |
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RPU54157-1mg | Biomatik Corporation | 1mg | EUR 2566.2 |
Recombinant Myoglobin (MYO) |
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RPU54157-50ug | Biomatik Corporation | 50ug | EUR 465.3 |
Recombinant Myoglobin (MYO) |
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RPU53908-100ug | Biomatik Corporation | 100ug | EUR 566.5 |
Recombinant Myoglobin (MYO) |
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RPU53908-1mg | Biomatik Corporation | 1mg | EUR 2511.6 |
Recombinant Myoglobin (MYO) |
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RPU53908-50ug | Biomatik Corporation | 50ug | EUR 455.4 |
Recombinant Myoglobin (MYO) |
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RPU42863-100ug | Biomatik Corporation | 100ug | EUR 431.2 |
Recombinant Myoglobin (MYO) |
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RPU42863-1mg | Biomatik Corporation | 1mg | EUR 1911 |
Recombinant Myoglobin (MYO) |
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RPU42863-50ug | Biomatik Corporation | 50ug | EUR 346.5 |
Recombinant Myoglobin (MYO) |
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RPU42864-100ug | Biomatik Corporation | 100ug | EUR 492.8 |
Recombinant Myoglobin (MYO) |
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RPU42864-1mg | Biomatik Corporation | 1mg | EUR 2184 |
Recombinant Myoglobin (MYO) |
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RPU42864-50ug | Biomatik Corporation | 50ug | EUR 396 |
Recombinant Myoglobin (MYO) |
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RPU42865-100ug | Biomatik Corporation | 100ug | EUR 517 |
Recombinant Myoglobin (MYO) |
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RPU42865-1mg | Biomatik Corporation | 1mg | EUR 2293.2 |
Recombinant Myoglobin (MYO) |
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RPU42865-50ug | Biomatik Corporation | 50ug | EUR 415.8 |
Recombinant Myoglobin (MYO) |
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RPU55533-100ug | Biomatik Corporation | 100ug | EUR 712.8 |
Recombinant Myoglobin (MYO) |
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RPU55533-1mg | Biomatik Corporation | 1mg | EUR 2808 |
Recombinant Myoglobin (MYO) |
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RPU55533-50ug | Biomatik Corporation | 50ug | EUR 432 |
Recombinant Myoglobin (MYO) |
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RPU56742-100ug | Biomatik Corporation | 100ug | EUR 470.4 |
Recombinant Myoglobin (MYO) |
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RPU56742-1mg | Biomatik Corporation | 1mg | EUR 2184 |
Recombinant Myoglobin (MYO) |
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RPU56742-50ug | Biomatik Corporation | 50ug | EUR 385 |
Recombinant Myoglobin (MYO) |
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RPU56743-100ug | Biomatik Corporation | 100ug | EUR 470.4 |
Recombinant Myoglobin (MYO) |
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RPU56743-1mg | Biomatik Corporation | 1mg | EUR 2184 |
Recombinant Myoglobin (MYO) |
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RPU56743-50ug | Biomatik Corporation | 50ug | EUR 385 |
Recombinant Myoglobin (MYO) |
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RPU54460-100ug | Biomatik Corporation | 100ug | EUR 601.7 |
Recombinant Myoglobin (MYO) |
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RPU54460-1mg | Biomatik Corporation | 1mg | EUR 2665 |
Recombinant Myoglobin (MYO) |
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RPU54460-50ug | Biomatik Corporation | 50ug | EUR 482.9 |
Recombinant Myoglobin (MYO) |
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RPU54498-100ug | Biomatik Corporation | 100ug | EUR 603.9 |
Recombinant Myoglobin (MYO) |
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RPU54498-1mg | Biomatik Corporation | 1mg | EUR 2675.4 |
Recombinant Myoglobin (MYO) |
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RPU54498-50ug | Biomatik Corporation | 50ug | EUR 485.1 |
Recombinant Myoglobin (MYO) |
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RPA480Bo01 | Cloud-Clone | 10ug | EUR 196 |
Recombinant Myoglobin (MYO) |
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4-RPA480Bo01 | Cloud-Clone |
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Description: Recombinant Bovine Myoglobin expressed in: E.coli |
Recombinant Myoglobin (MYO) |
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RPA480Eq01 | Cloud-Clone | 10ug | EUR 180 |
Recombinant Myoglobin (MYO) |
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4-RPA480Eq01 | Cloud-Clone |
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Description: Recombinant Horse Myoglobin expressed in: E.coli |
Recombinant Myoglobin (MYO) |
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RPA480Ga01 | Cloud-Clone | 10ug | EUR 195 |
Recombinant Myoglobin (MYO) |
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4-RPA480Ga01 | Cloud-Clone |
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Description: Recombinant Chicken Myoglobin expressed in: E.coli |
Recombinant Myoglobin (MYO) |
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RPA480Hu01 | Cloud-Clone | 10ug | EUR 140 |
Recombinant Myoglobin (MYO) |
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4-RPA480Hu01 | Cloud-Clone |
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Description: Recombinant Human Myoglobin expressed in: E.coli |
Recombinant Myoglobin (MYO) |
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RPA480Hu02 | Cloud-Clone | 10ug | EUR 140 |
Recombinant Myoglobin (MYO) |
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RPA480Mu01 | Cloud-Clone | 10ug | EUR 160 |
Recombinant Myoglobin (MYO) |
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4-RPA480Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Myoglobin expressed in: E.coli |
Recombinant Myoglobin (MYO) |
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RPA480Ov01 | Cloud-Clone | 10ug | EUR 188 |
Recombinant Myoglobin (MYO) |
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4-RPA480Ov01 | Cloud-Clone |
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Description: Recombinant Sheep Myoglobin expressed in: E.coli |
Recombinant Myoglobin (MYO) |
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RPA480Po01 | Cloud-Clone | 10ug | EUR 184 |
Recombinant Myoglobin (MYO) |
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4-RPA480Po01 | Cloud-Clone |
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Description: Recombinant Pig Myoglobin expressed in: E.coli |
Recombinant Myoglobin (MYO) |
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RPA480Ra01 | Cloud-Clone | 10ug | EUR 168 |
Recombinant Myoglobin (MYO) |
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4-RPA480Ra01 | Cloud-Clone |
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Description: Recombinant Rat Myoglobin expressed in: E.coli |
myo-Inositol-d6 |
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I665996 | Toronto Research Chemicals | 25mg | EUR 800 |
myo-Inositol-d6 |
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I665997 | Toronto Research Chemicals | 10mg | EUR 242 |
Description: 68922-44-1 |
myo-Inositol Hexaacetate |
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I666000 | Toronto Research Chemicals | 1g | EUR 230 |
Description: 1254-38-2 |
myo-Inositol Hexanicotinate |
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I666070 | Toronto Research Chemicals | 1g | EUR 155 |
Description: 6556-11-2 |
Myosin (Myo) Antibody (APC) |
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20-abx179002 | Abbexa |
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Rat Myoglobin (MYO) Protein |
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20-abx068139 | Abbexa |
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Rat Myoglobin (MYO) Protein |
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20-abx168607 | Abbexa |
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Cow Myoglobin (MYO) Protein |
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20-abx166312 | Abbexa |
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Pig Myoglobin (MYO) Protein |
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20-abx167524 | Abbexa |
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Myosin (Myo) Antibody (Biotin) |
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20-abx273382 | Abbexa |
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Myoglobin (MYO) Antibody (APC) |
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20-abx177666 | Abbexa |
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Myoglobin (MYO) Antibody (FITC) |
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20-abx271145 | Abbexa |
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Myoglobin (MYO) Antibody (FITC) |
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20-abx274004 | Abbexa |
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Myoglobin (MYO) Antibody (FITC) |
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20-abx274139 | Abbexa |
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Myoglobin (MYO) Antibody Pair |
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20-abx370147 | Abbexa |
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Human Myoglobin (MYO) Protein |
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20-abx068137 | Abbexa |
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Mouse Myoglobin (MYO) Protein |
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20-abx068138 | Abbexa |
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Sheep Myoglobin (MYO) Protein |
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20-abx168569 | Abbexa |
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Rabbit Myoglobin (MYO) Protein |
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20-abx654443 | Abbexa |
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Myoglobin (MYO) Antibody (Biotin) |
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20-abx271411 | Abbexa |
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Myoglobin (MYO) Antibody (Biotin) |
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20-abx272621 | Abbexa |
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Myoglobin (MYO) Antibody (Biotin) |
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20-abx273110 | Abbexa |
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Chicken Myoglobin (MYO) Protein |
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20-abx166370 | Abbexa |
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Myosin (Myo) Polyclonal Antibody |
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CAU30134-100ul | Biomatik Corporation | 100ul | EUR 281.3 |
Myosin (Myo) Polyclonal Antibody |
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CAU30134-200ul | Biomatik Corporation | 200ul | EUR 351.1 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27824-100ul | Biomatik Corporation | 100ul | EUR 229.4 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27824-200ul | Biomatik Corporation | 200ul | EUR 287.3 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27825-100ul | Biomatik Corporation | 100ul | EUR 254.4 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27825-200ul | Biomatik Corporation | 200ul | EUR 317.5 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27826-100ul | Biomatik Corporation | 100ul | EUR 271.7 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27826-200ul | Biomatik Corporation | 200ul | EUR 339.4 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27827-100ul | Biomatik Corporation | 100ul | EUR 217.9 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27827-200ul | Biomatik Corporation | 200ul | EUR 272.2 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27828-100ul | Biomatik Corporation | 100ul | EUR 241 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27828-200ul | Biomatik Corporation | 200ul | EUR 300.7 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27829-100ul | Biomatik Corporation | 100ul | EUR 229.4 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27829-200ul | Biomatik Corporation | 200ul | EUR 287.3 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27830-100ul | Biomatik Corporation | 100ul | EUR 254.4 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU27830-200ul | Biomatik Corporation | 200ul | EUR 317.5 |
Myoglobin (MYO) Monoclonal Antibody |
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CAU30633-100ul | Biomatik Corporation | 100ul | EUR 194.9 |
Myoglobin (MYO) Monoclonal Antibody |
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CAU30633-200ul | Biomatik Corporation | 200ul | EUR 243.6 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU31081-100ul | Biomatik Corporation | 100ul | EUR 229.4 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU31081-200ul | Biomatik Corporation | 200ul | EUR 287.3 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU31082-100ul | Biomatik Corporation | 100ul | EUR 241.9 |
Myoglobin (MYO) Polyclonal Antibody |
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CAU31082-200ul | Biomatik Corporation | 200ul | EUR 302.4 |
Myoglobin (MYO) Monoclonal Antibody |
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CAU32001-100ul | Biomatik Corporation | 100ul | EUR 267.8 |
Myoglobin (MYO) Monoclonal Antibody |
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CAU32001-200ul | Biomatik Corporation | 200ul | EUR 334.3 |
1,3,5-O-Methylidyne-myo-inositol |
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M312940 | Toronto Research Chemicals | 2.5g | EUR 1694 |
Description: 98510-20-4 |
human Myo,His tag |
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E4A10G05 | EnoGene | 50ug | EUR 255 |
Description: Available in various conjugation types. |
Myo ELISA KIT|Human |
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EF000262 | Lifescience Market | 96 Tests | EUR 826.8 |
myo-Inositol-2-d |
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I665998 | Toronto Research Chemicals | 100mg | EUR 3000 |
Description: NA |
Sodium/myo-Inositol Transporter 1 (SMIT1) Antibody |
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20-abx121741 | Abbexa |
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Pig Myosin (MYO) ELISA Kit |
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abx355156-96tests | Abbexa | 96 tests | EUR 990 |
Rat Myosin (MYO) ELISA Kit |
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abx255837-96tests | Abbexa | 96 tests | EUR 848.4 |
Rat Myosin(Myo) ELISA Kit |
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NSL0297r | Sunlong | 96 Tests | EUR 498 |
myo-Inositol, Animal-Free |
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13051-82 | NACALAI TESQUE | 25G | EUR 32.9 |
OACD05844-1ML - MYO Antibody |
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OACD05844-1ML | Aviva Systems Biology | 1ml | EUR 659 |
OACD05845-1ML - MYO Antibody |
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OACD05845-1ML | Aviva Systems Biology | 1ml | EUR 729 |
OACD05846-1ML - MYO Antibody |
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OACD05846-1ML | Aviva Systems Biology | 1ml | EUR 779 |
Human Myosin (Myo) CLIA Kit |
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20-abx496248 | Abbexa |
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Goat Myosin(Myo) ELISA Kit |
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NSL0382Gt | Sunlong | 96T | EUR 528 |
Pig Myoglobin (MYO) CLIA Kit |
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EKU08872-48T | Biomatik Corporation | 48T | EUR 799.82 |
Pig Myoglobin (MYO) CLIA Kit |
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EKU08872-5x96T | Biomatik Corporation | 5x96T | EUR 5427.35 |
Pig Myoglobin (MYO) CLIA Kit |
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EKU08872-96T | Biomatik Corporation | 96T | EUR 1142.6 |
Rat Myoglobin (MYO) CLIA Kit |
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EKU08873-48T | Biomatik Corporation | 48T | EUR 724.22 |
Rat Myoglobin (MYO) CLIA Kit |
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EKU08873-5x96T | Biomatik Corporation | 5x96T | EUR 4914.35 |
Rat Myoglobin (MYO) CLIA Kit |
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EKU08873-96T | Biomatik Corporation | 96T | EUR 1034.6 |
Human MYO (Myosin) ELISA Kit |
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EKE60856-5x96T | Biomatik Corporation | 5x96T | EUR 3124.08 |
Human MYO (Myosin) ELISA Kit |
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EKE60856-96T | Biomatik Corporation | 96T | EUR 657.7 |
Pig Myoglobin (MYO) CLIA Kit |
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EKN49983-48T | Biomatik Corporation | 48T | EUR 497.84 |
Pig Myoglobin (MYO) CLIA Kit |
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EKN49983-5x96T | Biomatik Corporation | 5x96T | EUR 3378.2 |
Pig Myoglobin (MYO) CLIA Kit |
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EKN49983-96T | Biomatik Corporation | 96T | EUR 711.2 |
Rat Myoglobin (MYO) CLIA Kit |
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EKN49984-48T | Biomatik Corporation | 48T | EUR 450.45 |
Rat Myoglobin (MYO) CLIA Kit |
|||
EKN49984-5x96T | Biomatik Corporation | 5x96T | EUR 3056.63 |
Rat Myoglobin (MYO) CLIA Kit |
|||
EKN49984-96T | Biomatik Corporation | 96T | EUR 643.5 |
Human Myosin (Myo) ELISA Kit |
|||
EKN47224-48T | Biomatik Corporation | 48T | EUR 302.61 |
Human Myosin (Myo) ELISA Kit |
|||
EKN47224-5x96T | Biomatik Corporation | 5x96T | EUR 2053.43 |
Human Myosin (Myo) ELISA Kit |
|||
EKN47224-96T | Biomatik Corporation | 96T | EUR 432.3 |
Human Myosin (Myo) ELISA Kit |
|||
EKU06113-48T | Biomatik Corporation | 48T | EUR 444.5 |
Human Myosin (Myo) ELISA Kit |
|||
EKU06113-5x96T | Biomatik Corporation | 5x96T | EUR 3016.25 |
Human Myosin (Myo) ELISA Kit |
|||
EKU06113-96T | Biomatik Corporation | 96T | EUR 635 |
Human Myosin (MYO) ELISA Kit |
|||
abx571452-96tests | Abbexa | 96 tests | EUR 943.2 |
Mouse Myosin (MYO) ELISA Kit |
|||
abx350887-96tests | Abbexa | 96 tests | EUR 943.2 |
Human Myosin (MYO) ELISA Kit |
|||
abx051336-96tests | Abbexa | 96 tests | EUR 943.2 |
Mouse Myosin (MYO) ELISA Kit |
|||
abx051337-96tests | Abbexa | 96 tests | EUR 943.2 |
Rat Myoglobin (MYO) CLIA Kit |
|||
20-abx190624 | Abbexa |
|
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Pig Myoglobin (MYO) CLIA Kit |
|||
20-abx190812 | Abbexa |
|
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Rat Myoglobin (MYO) CLIA Kit |
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abx195993-96tests | Abbexa | 96 tests | EUR 990 |
Human Myosin (Myo) ELISA Kit |
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20-abx152440 | Abbexa |
|
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Human Myosin ELISA Kit (Myo) |
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RK01913 | Abclonal | 96 Tests | EUR 625.2 |
Human Myosin(Myo) ELISA Kit |
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NSL0413Hu | Sunlong | 96 wells | EUR 468 |
CLIA Kit for Myoglobin (MYO) |
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SCA480Hu | Cloud-Clone | 96Т | EUR 840 |
CLIA Kit for Myoglobin (MYO) |
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SCA480Mu | Cloud-Clone | 96Т | EUR 864 |
CLIA Kit for Myoglobin (MYO) |
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SCA480Po | Cloud-Clone | 96Т | EUR 1008 |
Pig Myoglobin (MYO)CLIA Kit |
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SCA480Po-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 8096.83 |
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Pig Myoglobin (MYO) in serum, plasma, tissue homogenates and other biological fluids. |
Pig Myoglobin (MYO)CLIA Kit |
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SCA480Po-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 771.97 |
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Pig Myoglobin (MYO) in serum, plasma, tissue homogenates and other biological fluids. |
Pig Myoglobin (MYO)CLIA Kit |
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SCA480Po-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 1051.39 |
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Pig Myoglobin (MYO) in serum, plasma, tissue homogenates and other biological fluids. |
The total estimated dietary intakes of the considered classes of compounds through insect consumption are comparable with those generally assessed in common food of animal origin worldwide and, when compared with existing reference dose values, suggest that the risk of adverse health effects from exposure to the targeted organic compounds via insect consumption is unlikely. https://doi.org/10.1289/EHP5782.